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Rexblad 15 SR ( Oxybutynin Chloride )

  • Effective Material
    Oxybutynin Chloride 15 mg
  • Caliber
    15 mg
  • Pharmacologic Form
    - Muscarinic antagonist
  • Therapeutic Categories
    Urological Drugs
  • Pharmaceutical Form
    F.C. Tablets
Each tablet of Rexblad 15 SR Contains: Oxybutynin Chloride 15mg.
Side effect
Diarrhea, hypotension, Headache, Nasopharyngitis, Nasal Congestion, Retrograde Ejaculation.
Pharmacodynamics properties
Oxybutynin chloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. Oxybutynin chloride relaxes bladder smooth muscle. In patients with conditions characterized by involuntary bladder contractions.
Therapeutic indications
This drug is indicated for the relief of symptoms of bladder instability associated with voiding in patients with neurogenic bladder (i.e., urgency, frequency, urinary leakage, urge incontinence, dysuria).
• Urinary retention, gastric retention
• Uncontrolled narrow-angle glaucoma
• Hypersensitivity to the drug substance or other components of the product.
Warnings and precautions
This drug should be used with caution in the frail elderly, in patients with hepatic or renal impairment, and in patients with myasthenia gravis, and patients with clinically significant bladder outflow obstruction. It should be administered with caution to patients with gastrointestinal obstructive disorders.
Drug interactions
The concomitant use of oxybutynin with other anticholinergic drugs or with other agents which produce dry mouth, constipation, somnolence (drowsiness) may increase the frequency and/or severity of such effects.
Dosage and Method of administration
The usual dose is one teaspoon (5 mg/5 mL) of syrup two to three times a day. The maximum recommended dose is one teaspoon (5 mg/5 mL) of syrup four times a day. A lower starting dose of 2.5 mg two or three times a day is recommended for the frail elderly.
Pediatric patients over 5 years of age
The usual dose is one teaspoon (5 mg/5 mL) of syrup two times a day. The maximum recommended dose is one teaspoon (5 mg/5mL) of syrup three times a day.
Treatment should be symptomatic and supportive. Activated charcoal as well as a cathartic may be administered.