Composition |
Sun-D3 10000 contains 10000 IU of vitamin D3 (Colecalciferol). |
Pharmacokinetics |
Distribution: Primarily hepatic Protein binding: Extensively to vitamin D-binding protein Metabolism: Primary liver and kidney hydroxylation; glucuronidation. Half-life elimination: 14 hours. Time to peak, plasma: 11 hours. Excretion: As metabolites, urine (4.2 %) and feces (4.9 %). |
Therapeutic indications |
- Treatment of vitamin D deficiency. - Dietary supplement for the treatment and prophylaxis of osteoporosis. - Prophylaxis of deficiency (recent studies shown that vitamin D3 deficiency more prevalence in a lot of patients, and it’s strong relationship with diseases of elderly, women, and cardiovascular diseases, diabetes mellitus, hypertension, Multiple sclorosis, cancer. |
Side effect |
Frequency not defined: Hypervitaminosis D (signs and symptoms include increase in blood phosphate or hypercalcemia, calciuria, headache, nausea, vomiting, vertigo, lethargy, polyuria, diarrhea or constipation and polydipsia).. |
Contraindication |
Hypercalcemia; hypersensitivity to cholecalciferol or any component of the formulation; malabsorption syndrome; evidence of vitamin D toxicity |
Warnings & precautions |
The levels of plasma calcium should be monitored especially in patients who are vulnerable to hypercalcemia. |
Pregnancy & lactation |
PREGNANCY: Pregnancy Category C.
NURSING MOTHERS: Enters breast milk. should be used cautiously during lactation. |
Drug interactions |
- Don't co-administer with Orlistat or Olestra. - Ethanol, Nutrition, and herbs may impair vitamin D absorption. - People who use cardiac glycosides (digoxin) or thiazide diuretics should consult a physician before using supplemental vitamin D. - Some antiepileptics increase vitamin D demand such as: carbamazepine, phenytoin, and Phenobarbital. - Fat malabsorption decreases vitamin D absorption. |
Dosage & administration |
Sun-D3 10000: Take one capsule weekly. or as recommended by a the physician. |
Package |
Sun-D3 5000: 1 blisters x 10 Capsules per Box with inserted leaflets. |
Storage |
Store at 15-30°C. Keep away from reach of children. |